Figure 1

Schematic representation of endothelial functions in physiological states. FVIIa, activated factor VII; FVi, inactivated factor V; TF, tissue factor; AT-III, antithrombin-III; TFPI, tissue factor pathway inhibitor; PC, protein C; APC, activated protein C; PS, protein S; TM, thrombomodulin; EPCR, endothelial protein C receptor; NO, nitrate oxide; PGI2, prostaglandin I2.