Fig. 1
From: Renal replacement therapy neutralizes elevated MIF levels in septic shock

MIF removal from circulating plasma pool of septic patients by CVVHD is associated with an improved outcome. a Septic patients undergoing CRRT due to septic acute kidney injury showed lower MIF levels compared to septic patients without the need for CRRT during ICU stay. b Total MIF release during ICU stay as assessed by MIFAUC was lower in patients undergoing CRRT compared to those without the need for CRRT. c Kaplan-Meier survival curves show increased 30-day mortality for patients without CRRT compared to those undergoing CRRT