| Ees [mmHg/mL] | EaInsp [mmHg/mL] | EaExp [mmHg/mL] |
---|
Intercept | 0.83 [0.66 to 1.00] | 0.37 [0.03 to 0.71] | 0.39 [0.30 to 0.49] |
HPV | 1.36 [1.21 to 1.51]‡ | 0.89 [0.51 to 1.27]‡ | 0.75 [0.67 to 0.84]‡ |
PE | 0.44 [0.29 to 0.59]‡ | − 0.35 [− 0.73 to 0.02] | 0.36 [0.27 to 0.44]‡ |
QECMO | 0.07 [0.03 to 0.10]‡ | 0.30 [0.21 to 0.39]‡ | 0.04 [0.02 to 0.06]‡ |
QECMO × HPV | − 0.03 [− 0.09 to 0.02] | − 0.12 [− 0.26 to 0.02] | 0.00 [− 0.03 to 0.03] |
QECMO × PE | 0.07 [0.01 to 0.12]* | 0.65 [0.51 to 0.79]‡ | 0.01 [− 0.03 to 0.04] |
Adjusted r2 | 0.69 | 0.45 | 0.69 |
- Estimates from regression are shown with 95% CI. The intercept is the estimated value at 0 L/min QECMO at baseline. HPV and PE estimates the change if the respective condition is present. QECMO estimates the change per change of 1 L/min. QECMO × HPV and QECMO × PE estimates the additional change per change of 1 L/min of QECMO during the respective condition. Inspiratory (Insp) and expiratory (exp) refer to the cardiac cycle with minimal and maximal stroke volumes, respectively. QECMO: ECMO blood flow [L/min]. HPV: hypoxic pulmonary vasoconstriction. PE: pulmonary embolism. Ees: ventricular elastance. Ea: arterial elastance. *p < 0.05. ‡p < 0.001