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Table 2 Estimates from linear mixed-effect models predicting right ventricular indices and ventricular–arterial coupling

From: Mechanisms maintaining right ventricular contractility-to-pulmonary arterial elastance ratio in VA ECMO: a retrospective animal data analysis of RV–PA coupling

 

Ees [mmHg/mL]

EaInsp [mmHg/mL]

EaExp [mmHg/mL]

Intercept

0.83 [0.66 to 1.00]

0.37 [0.03 to 0.71]

0.39 [0.30 to 0.49]

HPV

1.36 [1.21 to 1.51]

0.89 [0.51 to 1.27]

0.75 [0.67 to 0.84]

PE

0.44 [0.29 to 0.59]

− 0.35 [− 0.73 to 0.02]

0.36 [0.27 to 0.44]

QECMO

0.07 [0.03 to 0.10]

0.30 [0.21 to 0.39]

0.04 [0.02 to 0.06]

QECMO × HPV

− 0.03 [− 0.09 to 0.02]

− 0.12 [− 0.26 to 0.02]

0.00 [− 0.03 to 0.03]

QECMO × PE

0.07 [0.01 to 0.12]*

0.65 [0.51 to 0.79]

0.01 [− 0.03 to 0.04]

Adjusted r2

0.69

0.45

0.69

  1. Estimates from regression are shown with 95% CI. The intercept is the estimated value at 0 L/min QECMO at baseline. HPV and PE estimates the change if the respective condition is present. QECMO estimates the change per change of 1 L/min. QECMO × HPV and QECMO × PE estimates the additional change per change of 1 L/min of QECMO during the respective condition. Inspiratory (Insp) and expiratory (exp) refer to the cardiac cycle with minimal and maximal stroke volumes, respectively. QECMO: ECMO blood flow [L/min]. HPV: hypoxic pulmonary vasoconstriction. PE: pulmonary embolism. Ees: ventricular elastance. Ea: arterial elastance. *p < 0.05. p < 0.001