Fig. 3

Graphs A–C show the effects of cecal ligation and puncture (CLP) in 5/6 nephrectomy (Nx) or control rats on the low-frequency component (LFnu), high-frequency component (HFnu), and LF/HF ratio obtained by analysis of heart rate data obtained by electrocardiographic telemetry. Graph D shows the effects of CLP in Nx or control rats on the urinary norepinephrine excretion level based on a 24-h urine collection. Data are expressed as mean ± SEM; sham-sham (n = 5), sham-CLP (n = 8), Nx-sham (n = 5), and Nx-CLP (n = 9) groups. *p < 0.01 compared with control groups, and ^#p < 0.05 compared with sham-CLP groups. Graph E shows the time course (day1, day2) of the LF/HF ratio in Nx or sham-operated rats before and after the CLP procedure. Data are expressed as mean ± SEM. Two-way ANOVA with multiple comparisons, **p < 0.01, compared with each control, and ^†p < 0.05, compared with sham-CLP. SEM standard error of the mean, ANOVA analysis of variance