Table 3 Baseline characteristics of patients with NIV intolerance prior to treatment
Variables | Total (n = 179) | REM group (n = 89) | DEX group (n = 90) | p value |
|---|---|---|---|---|
Reasons for NIV | 0.097 | |||
 Cardiogenic, n (%) | 99 (55.31) | 55 (61.80) | 44 (49.44) |  |
 Noncardiogenic, n (%) | 79 (44.13) | 34 (38.20) | 45 (50.56) |  |
Duration from ICU admission to NIV (h) | 58.7 (37.5, 115.0) | 61.0 (38.0, 128.0) | 52.3 (36.0, 93.0) | 0.369 |
NIV parameters | ||||
 Vt, ml | 525 (480, 574) | 523 (483, 567) | 531 (475, 578) | 0.502 |
 PS, cmH2O | 12 (10, 12) | 12 (10, 12) | 12 (10, 12) | 0.724 |
 PEEP, cmH2O | 5 (5, 6) | 5 (5, 6) | 5 (5, 6) | 0.695 |
 FiO2, % | 60 (50, 70) | 60 (50, 70) | 60 (50, 80) | 0.127 |
VAS, points | 3 (2, 3) | 3 (2, 3) | 3 (2, 3) | 0.992 |
NIS, points | 3 (3, 3) | 3 (3, 3) | 3 (3, 3) | 0.180 |
Vital signs | ||||
 Temperature, °C | 37 (36.8, 37.7) | 37.2 (36.9, 37.8) | 37 (36.7, 37.5) | 0.024 |
 RR, breaths/min | 27 ± 9 | 26 ± 5 | 28 ± 11 | 0.515 |
 HR, bpm | 93 (83,105) | 93 (83, 104) | 91 (81,105) | 0.523 |
 SBP, mmHg | 125 (114,141) | 125 (113,140) | 125 (116,145) | 0.536 |
 DBP, mmHg | 63 ± 11 | 63 ± 11 | 63 ± 11 | 0.842 |
 MAP, mmHg | 82 (75, 90) | 81(75, 90) | 83(76, 90) | 0.577 |
 SpO2, % | 98 (96, 100) | 98 (96, 99) | 98 (96, 100) | 0.425 |
CVP, mmHg | 12(10, 14) | 12 (10, 14) | 12 (11, 14) | 0.831 |
PaO2, mmHg | 94.5(74.50,140.85) | 94.05(76.75,140.95) | 95.3(72.70,139.75) | 0.824 |
PaCO2, mmHg | 38.3(34.10,43.75) | 38.45(34.55,43.30) | 37.85(34.05,44.20) | 0.929 |
Laboratory test | ||||
 Hb, g/L | 90 (82.00, 101.00) | 90 (81.50, 99.00) | 90 (83.00, 103.00) | 0.655 |
 WBC, *109/L | 11.47 (8.34, 14.03) | 10.84 (8.39, 13.31) | 11.94 (8.34, 14.64) | 0.302 |
 PLT, *109/L | 104 (75, 154) | 103.5 (69, 150) | 106 (83, 157) | 0.180 |
 ALT, U/L | 20 (12.00, 36.50) | 21.5 (13.50, 46.50) | 19 (12.00, 30.50) | 0.206 |
 AST, U/L | 37 (24.50, 61.00) | 42 (25.50, 62.00) | 34 (23.50, 59.00) | 0.210 |
 TBIL, μmol/L | 19.7 (12.80, 30.00) | 21.25 (14.30, 30.30) | 18.95 (12.20, 29.35) | 0.194 |
 DBIL, μmol/L | 9.1 (5.70, 16.25) | 9.3 (6.20, 16.20) | 8.75 (5.34, 16.95) | 0.267 |
 CR, μmol/L | 106 (81.0, 158.0) | 114 (81.0, 158.0) | 104 (80.5, 160.0) | 0.818 |
 NT-proBNP, pg/ml | 2283 (1146, 5201) | 2850 (1270, 6074) | 1958 (1104, 4581) | 0.092 |
 cTnT, ng/ml | 0.43 (0.21, 0.90) | 0.59 (0.24, 1.00) | 0.36 (0.19, 0.83) | 0.252 |
LVEF, % | 62 (55, 66) | 62 (53, 66) | 61 (55, 66) | 0.924 |