Monte Carlo simulations of cefepime in children receiving continuous kidney replacement therapy support continuous infusions for target attainment

Table 1 Comparison of PTA for artificial vs real-world patients with eGFR 5 mL/min/1.73 m²

CI, continuous infusion. EI, 4 h extended infusion. SI, 30-min standard infusion. Numbers in colored boxes represent the percent of 1000-fold simulated patients who achieved 100% fT > MIC. Results presented for artificial patients were with Q_ef 2500 mL/min/1.73 m² averaged across all four fluid accumulation categories, given similar means in fluid accumulation between both groups as shown in this Table. Results for real-world patients were using actual Q_ef and fluid accumulation

ISSN: 2052-0492