Table 1 Baseline characteristics of patients with severe respiratory failure on mechanical ventilation
Unmatched groups | Propensity score-matched groups | |||||
|---|---|---|---|---|---|---|
Certified (n = 30,588) | Non-certified (n = 36,317) | ASD | Certified (n = 26,673) | Non-certified (n = 26,673) | ASD | |
Age, years | 73 (62–81) | 77 (69–84) | 0.326 | 75 (65–82) | 75 (66–83) | 0.046 |
Male sex, n (%) | 19,745 (65) | 22,982 (63) | 0.026 | 17,170 (64) | 17,221 (65) | 0.004 |
Body mass index, kg/m2 | 21 (18–24) | 20 (18–23) | 0.125 | 20 (18–24) | 21 (18–24) | 0.029 |
Emergency admission, n (%) | 29,154 (95) | 34,215 (94) | 0.049 | 25,332 (95) | 25,298 (95) | 0.006 |
Ambulance use, n (%) | 22,555 (74) | 22,645 (62) | 0.248 | 19,029 (72) | 18,921 (71) | 0.010 |
Smoking, n (%) | 9357 (38) | 11,603 (37) | 0.018 | 8145 (37) | 8708 (38) | 0.006 |
Diagnosis associated with acute respiratory diseasea, n (%) | ||||||
Bacterial pneumonia | 11,869 (39) | 12,730 (35) | 0.078 | 9984 (37) | 9815 (37) | 0.013 |
Interstitial pneumonia | 4038 (13) | 4934 (14) | 0.011 | 3649 (14) | 3753 (14) | 0.011 |
ARDS | 2492 (8.1) | 2778 (7.6) | 0.018 | 2161 (8.1) | 2172 (8.1) | 0.002 |
Allergic | 1837 (6.0) | 3082 (8.5) | 0.096 | 1743 (6.5) | 1785 (6.7) | 0.006 |
Viral pneumonia | 2020 (6.6) | 2012 (5.5) | 0.045 | 1694 (6.4) | 1635 (6.1) | 0.009 |
Tuberculosis | 549 (1.8) | 1003 (2.8) | 0.065 | 522 (2.0) | 532 (2.0) | 0.003 |
Mycobacterium avium complex | 269 (0.9) | 515 (1.4) | 0.051 | 263 (1.0) | 261 (1.0) | 0.001 |
Aspergillus | 342 (1.1) | 358 (1.0) | 0.013 | 286 (1.1) | 281 (1.1) | 0.002 |
Pneumocystis pneumonia | 323 (1.1) | 229 (0.6) | 0.047 | 248 (0.9) | 215 (0.8) | 0.013 |
Any pneumonia or bronchitisb | 21,790 (71) | 26,374 (73) | 0.031 | 19,169 (72) | 19,238 (72) | 0.006 |
Vasopressors on MV Day 1, n (%) | 11,037 (36) | 8787 (24) | 0.261 | 8631 (32) | 8187 (31) | 0.036 |
ECMO on MV Day 1, n (%) | 21 (0.1) | 0 (0) | 0.037 | 14 (0.1) | 0 (0) | 0.032 |