Fig. 2

Relationship between FBgap and %TTL stratified by total alarms. FBgap, fluid balance gap; %TTL, percent treatment time loss; CCI, Charlson comorbidity index; SOFA, sequential organ failure assessment; CRRT, continuous renal replacement therapy; MV, mechanical ventilation; IABP, intra-aortic balloon pump; VAD, ventricular assist device; ECMO, extracorporeal membrane oxygenation. Adjusted FBgap was calculated based on the multivariate linear regression model with FBgap as the dependent variable and %TTL, along with age, sex, race, CCI, SOFA score at CRRT initiation, use of MV at CRRT initiation, use of circulatory support devices (any of IABP, VAD, ECMO) at CRRT initiation, and %fluid overload as independent variables