Association of continuous renal replacement therapy downtime with fluid balance gap and clinical outcomes: a retrospective cohort analysis utilizing EHR and machine data

Table 2 Clinical and process outcomes stratified by %TTL tertiles

		Overall	%TTL lowest tertile	%TTL middle tertile	%TTL highest tertile
Hospital mortality	n (%)	271 (54.2)	98 (58.7)	89 (53.6)	84 (50.3)
Length of hospital stay (days)	Median [IQR]	15 [7, 28]	12 [5, 24]	17 [9, 29]	16 [9, 30]
Length of ICU stay (days)	Median [IQR]	10 [5, 19]	6 [3, 13]	12 [7, 21]	12 [7, 21]
Total CRRT duration (days)	Median [IQR]	5 [3, 9]	4 [2, 6]	7 [4, 11]	5 [3, 11]
ICU-free days	Median [IQR]	0 [0, 4]	0 [0, 11]	0 [0, 0]	0 [0, 4]
CRRT-free days	Median [IQR]	0 [0, 14]	0 [0, 21]	0 [0, 12]	0 [0, 15]
MV-free days	Median [IQR]	0 [0, 14]	0 [0, 16]	0 [0, 6]	0 [0, 16]
Cardiac support device-free days	Median [IQR]	0 [0, 28]	0 [0, 28]	0 [0, 28]	0 [0, 28]

The outcome of free days indicates the number of days within the 28-day period after CRRT initiation during which there was no exposure to each respective factor. If the patient died within the 28 days, the number of free days is treated as 0
ICU, intensive care unit; CRRT, continuous renal replacement therapy; MV, mechanical ventilation; IQR, interquartile range

ISSN: 2052-0492