Fig. 3
From: Impact of hyper- and hypothermia on cellular and whole-body physiology
Leukocyte cell death induced by hyperthermia. Leukocytes obtained from rats were exposed to heat (42.0 °C) in vitro, and their morphological changes observed under a microscope using 4′,6-diamidino-2-phenylindole (DAPI) staining. Apoptotic cells showed cytoplasmic shrinkage and fragmentation (arrows), while necrotic cells exhibited ballooning (arrowheads)