Fig. 5
From: Impact of hyper- and hypothermia on cellular and whole-body physiology

Mitochondrial damage under hyperthermia. Leukocytes obtained from rats were exposed to heat in vitro (42.0 °C). Mitochondria were stained using immunofluorescence [MitoBright LT ™, fluorescein isothiocyanate (FITC), green] and observed under a microscope. The intensity of mitochondrial staining diminished as the temperature increased, indicating a possible loss of mitochondrial integrity or function due to heat stress