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Table 2 Interpretation of certainty of evidence

From: The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2024

Certainty of evidence

Notation

Explanation

High

A

High confidence in the estimated value of effects

Moderate

B

Moderate confidence in the estimated value of effects

Low

C

Limited confidence in the estimated value of effects

Very low

D

Little confidence in the estimated value of effects