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Table 2 Questionnaire results

From: Two-year trajectory of functional recovery and quality of life in post-intensive care syndrome: a multicenter prospective observational study on mechanically ventilated patients with coronavirus disease-19

 

1st survey (n = 251)

2nd survey (n = 209)

3rd survey (n = 192)

4th survey (n = 178)

Physical function

    

 Barthel index, mean (SD)

92.4 (33.8)

94.7 (44.8)

93.6 (37)

94.4 (37.1)

  Self-care impairment, n (%)

41 (16.3)

25 (12.0)

16 (8.3)

16 (9.0)

  Excretion impairment, n (%)

37 (14.7)

23 (11.0)

26 (13.5)

23 (12.9)

  Transferring impairment, n (%)

20 (8.0)

9 (4.3)

10 (5.2)

8 (4.5)

  Movement impairment, n (%)

39 (15.5)

33 (15.8)

22 (11.5)

22 (12.4)

Cognitive function

    

 Short-Memory Questionnaire, mean (SD)

38.2 (13.9)

38.0 (20.2)

36.4 (15.4)

36.9 (15.7)

Mental health

    

 Anxiety (HADS-Anxiety score ≥ 8), n (%)

49 (19.5)

25 (12.0)

34 (17.7)

25 (14.0)

 Depression (HADS-Depression score ≥ 8), n (%)

49 (19.5)

35 (16.8)

38 (19.8)

36 (20.2)

 HADS score, mean (SD)

9.5 (8.4)

9.1 (12.0)

9.6 (10.0)

8.8 (8.0)

  HADS-Anxiety score

4.6 (4.3)

4.3 (5.9)

4.6 (5.2)

3.8 (3.9)

  HADS-Depression score

4.8 (4.7)

4.8 (6.5)

5.1 (5.4)

4.9 (4.8)

QOL

    

 EQ-5D-5L, mean (SD)

0.804 (0.336)

0.839 (0.410)

0.833 (0.356)

0.824 (0.359)

Visual analog scale, mean (SD)

    

 Physical function (on a scale of 1 to 10)

6.9 (2.2)

7.1 (2.0)

7.1 (2.0)

7.1 (1.9)

 Cognitive function (on a scale of 1 to 10)

8.2 (2.1)

8.0 (1.9)

7.9 (1.9)

8.0 (1.8)

 Mental health (on a scale of 1 to 10)

7.6 (2.3)

7.6 (2.3)

7.7 (2.2)

7.8 (1.9)

Others, n (%)

    

 Dyspnea

118 (47.0)

96 (45.9)

89 (46.4)

89 (50.0)

 Walking difficulty

89 (35.5)

54 (25.8)

55 (28.7)

57 (32.0)

 Weight loss

154 (61.4)

48 (23.0)

39 (20.3)

48 (27.0)

 Memory impairment

74 (29.5)

66 (31.6)

66 (34.4)

68 (38.2)

 Executive dysfunction

120 (47.8)

93 (44.5)

96 (50.0)

82 (46.1)

 Depression

103 (41.0)

81 (38.8)

71 (37.0)

70 (39.3)

 Anxiety

144 (57.4)

107 (51.2)

94 (49.0)

93 (52.3)

 Sleeping disorder

113 (45.0)

92 (44.0)

82 (42.7)

73 (41.0)

  1. EQ-5D-5L EuroQol 5 dimensions 5-level, HADS Hospital Anxiety and Depression Scale, QOL quality of life, SD standard deviation
  2. Outcome scores of Barthel index, Short-Memory Questionnaire, Hospital Anxiety and Depression Scale-Anxiety score, Hospital Anxiety and Depression Scale-Depression score, and EuroQol 5 dimensions 5-level were stabilized using inverse probability of censoring weights that take into account missing data. The included covariates were age, gender, BMI, SOFA score, clinical frailty scale, comorbidities (hypertension, diabetes, cardiac disease, chronic renal disease, autoimmune disease, malignancy, chronic obstructive pulmonary disease, immunodeficiency), reintubation, ECMO, tracheostomy, continuous neuromuscular blockade, supine position, maximum prednisolone equivalent daily dose, continuous renal replacement therapy, intermittent renal replacement therapy, rehabilitation, delirium, duration of mechanical ventilation, length of ICU stay, length of hospital stay, ICU duration, presence of family members, and use of an ICU diary