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Table 1 Patient characteristics

From: Association between initial intravenous fluid volume and the composite outcome of hemodialysis dependence at discharge or in-hospital mortality in inpatients with rhabdomyolysis

Characteristics

Overall patients

Before overlap weighting

After overlap weighting

IVF ≥ 3500 mL/day

IVF < 3500 mL/day

ASD

IVF ≥ 3500 mL/day

IVF < 3500 mL/day

ASD

Age, years, mean (SD)

66.8

(17.5)

61.1

(17.7)

69.5

(16.7)

0.49

(17.2)

 

(18.1)

 

0.03

Age, years, Median (IQR)

71

(56, 80)

64

(49, 76)

73

(60,82)

      

Male, n (%)

3512

(65.1)

1218

(72.6)

2294

(61.7)

0.23

(30.3)

 

(31.4)

 

0.02

Body mass index, kg/cm2, n (%)

      

0.21

    

0.04

 < 18.5

710

(13.2)

168

(11.4)

542

(16.7)

 

(13.1)

 

(13.1)

  

 18.5–24.9

2729

(50.6)

843

(57.1)

1886

(58.2)

 

(57.5)

 

(58.9)

  

 25.0–29.9

982

(18.2)

334

(22.6)

648

(20.0)

 

(21.7)

 

(21.0)

  

 ≥ 30.0

296

(5.5)

131

(8.9)

165

(5.1)

 

(7.8)

 

(7.0)

  

 Missing

675

(12.5)

201

(12.0)

474

(12.8)

      

Japanese Coma Scale, n (%)

      

0.13

    

0.03

 0 (alert)

2168

(40.2)

658

(39.2)

1510

(40.6)

 

(41.0)

 

(39.7)

  

 1-digit (dizziness)

2440

(45.3)

738

(44.0)

1702

(45.8)

 

(44.6)

 

(45.8)

  

 2-digit (somnolence)

519

(9.6)

165

(9.8)

354

(9.5)

 

(9.1)

 

(9.6)

  

 3-digit (coma)

265

(4.9)

116

(6.9)

149

(4.0)

 

(5.2)

 

(4.9)

  

Charlson Comorbidity Index, n (%)

      

0.17

    

0.05

 0

3925

(72.8)

1297

(77.3)

2628

(70.7)

 

(75.3)

 

(73.9)

  

 1

332

(6.2)

103

(6.1)

229

(6.2)

 

(6.6)

 

(6.6)

  

 2

923

(17.1)

227

(13.5)

696

(18.7)

 

(14.5)

 

(16.2)

  

 ≥ 3

212

(3.9)

50

(3.0)

162

(4.4)

 

(3.5)

 

(3.3)

  

Tertiary hospital admission, n (%)

4532

(84.1)

1269

(75.7)

3229

(86.9)

0.18

(83.0)

 

(84.8)

 

0.05

ICU admission, n (%)

946

(17.5)

399

(24.0)

547

(14.7)

0.23

(18.7)

 

(16.9)

 

0.05

Drug or device use (days 1–3), n (%)

            

 Mechanical ventilation

323

(6.0)

220

(13.1)

103

(2.8)

0.38

(6.6)

 

(5.9)

 

0.03

 High-flow nasal cannula

11

(0.2)

8

(0.5)

3

(0.1)

0.08

(0.2)

 

(0.2)

 

0.01

 Other oxygen device

2202

(40.8)

827

(49.3)

1375

(37.0)

0.25

(44.5)

 

(43.4)

 

0.02

 Hemodialysis

549

(10.2)

425

(25.3)

124

(3.3)

0.66

(9.6)

 

(9.0)

 

0.02

 Vasopressors

337

(6.3)

227

(13.5)

110

(3.0)

0.39

(6.4)

 

(6.1)

 

0.01

 Sodium bicarbonate

313

(5.8)

154

(9.2)

159

(4.3)

0.20

(6.1)

 

(6.6)

 

0.02

 Loop diuretics

894

(16.6)

408

(24.3)

486

(13.1)

0.29

(18.6)

 

(17.3)

 

0.03

 Lipid-lowering drugs

269

(5.0)

45

(2.7)

224

(6.0)

0.16

(3.6)

 

(3.7)

 

0.00

Disease, n (%)

            

 Infection

737

(13.7)

229

(13.7)

508

(13.7)

0.00

(12.2)

 

(12.7)

 

0.02

 Trauma

677

(12.6)

201

(12.0)

476

(12.8)

0.03

(11.8)

 

(12.0)

 

0.01

 Epilepsy

206

(3.8)

67

(4.0)

139

(3.7)

0.01

(4.1)

 

(4.4)

 

0.01

 Heatstroke

146

(2.7)

53

(3.2)

93

(2.5)

0.04

(3.0)

 

(2.9)

 

0.00

 CKD

126

(2.3)

24

(1.4)

102

(2.7)

0.09

(2.1)

 

(2.1)

 

0.00

 Hypothermia

133

(2.5)

48

(2.9)

85

(2.3)

0.04

(2.4)

 

(2.2)

 

0.01

 Neuroleptic malignant syndrome

103

(1.9)

46

(2.7)

57

(1.5)

0.08

(2.0)

 

(2.2)

 

0.01

 Hypothyroid

50

(0.9)

13

(0.8)

37

(1.0)

0.02

(0.8)

 

(0.8)

 

0.01

 Burn

34

(0.6)

20

(1.2)

14

(0.4)

0.09

(0.7)

 

(0.7)

 

0.00

 Drug intoxication

121

(2.2)

52

(3.1)

69

(1.9)

0.08

(2.8)

 

(2.8)

 

0.00

 Ethanol intoxication

12

(0.2)

5

(0.3)

7

(0.2)

0.02

(0.2)

 

(0.2)

 

0.01

 Diabetic ketoacidosis

9

(0.2)

5

(0.3)

4

(0.1)

0.04

(0.2)

 

(0.2)

 

0.00

 Severe asthma

3

(0.1)

2

(0.1)

1

(0.0)

0.03

(0.1)

 

(0.1)

 

0.00

 Maintenance fluid (days 1–3), mL, mean (SD)

1168

(7042)

808

(1453.9)

1331

(8423.5)

0.09

838

(1486)

995

(1470)

0.06

 Maintenance fluid (days 1–3), mL, median (IQR)

0

(0, 2000)

0

(0, 1000)

500

(0, 2000)

      
  1. ASD absolute standardized difference, CKD chronic kidney disease, ICU intensive care unit, IQR interquartile range, IVF intravenous fluid, SD standard deviation