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Table 1 Characteristics of the patients

From: One-year outcomes in sepsis: a prospective multicenter cohort study in Japan

Variable

Overall (n = 339)

Baseline characteristics

 Age (year)

74 [67–82]

 Sex (Male)

203 (60)

 Body Mass Index (kg/m2)

23.4 [20.4–25.8]

 Charlson Comorbidity Index

2 [1–3]

 Clinical Frailty Scale prior to hospital admission

3 [3–5]

 Barthel Index prior to hospital admission

100 [90–100]

 Employment status prior to hospital admission

80 (24)

ICU admission route

 ER

246 (73)

 General ward

85 (25)

 Others

8 (2)

Source of infection

 Abdomen

111 (32)

 Urinary tract

63 (19)

 Musculoskeletal and soft tissue

63 (19)

 Respiratory

57 (17)

 Other

45 (13)

 Sequential Organ Failure Assessment (SOFA) sum score

9 [6–12]

 Lactate level at ICU admission (mmol/L)

3.1 [1.6–5.8]

 Presence of septic shock at ICU admission

261 (77)

Use of vasoactive drugs during ICU stay

 Noradrenaline

298 (88)

 Vasopressin

145 (43)

 Epinephrine

42 (12)

 Use of medical devices during ICU stay

 Noninvasive positive pressure ventilation (NPPV)

27 (8)

 High flow nasal cannula (HFNC)

57 (17)

 Invasive mechanical ventilation (IMV)

208 (61)

 Renal replacement therapy (RRT)

136 (40)

Clinical consequences of hospital stay

 ICU mortality

39 (12)

 Duration of invasive mechanical ventilation

5.0 [2.8–10.0]

 Length of ICU stay (days)

6.1 [3.7–10.8]

 Length of Hospital stay (days)

28.7 [16.5–51.5]

Number of patients who met PICS criteria at hospital discharge

 Incidence of PICS

223 (66)

 Incidence of physical dysfunction

164 (48)

 Incidence of cognitive dysfunction

145 (43)

 Incidence of mental disorder

129 (38)

  1. The data in the table are presented as median with inter quartile range [IQR] or number with percentage (%)
  2. ICU Intensive Care Unit, PICS Post-Intensive Care Syndrome