From: One-year outcomes in sepsis: a prospective multicenter cohort study in Japan
Variable | Overall (n = 339) |
---|---|
Baseline characteristics | |
 Age (year) | 74 [67–82] |
 Sex (Male) | 203 (60) |
 Body Mass Index (kg/m2) | 23.4 [20.4–25.8] |
 Charlson Comorbidity Index | 2 [1–3] |
 Clinical Frailty Scale prior to hospital admission | 3 [3–5] |
 Barthel Index prior to hospital admission | 100 [90–100] |
 Employment status prior to hospital admission | 80 (24) |
ICU admission route | |
 ER | 246 (73) |
 General ward | 85 (25) |
 Others | 8 (2) |
Source of infection | |
 Abdomen | 111 (32) |
 Urinary tract | 63 (19) |
 Musculoskeletal and soft tissue | 63 (19) |
 Respiratory | 57 (17) |
 Other | 45 (13) |
 Sequential Organ Failure Assessment (SOFA) sum score | 9 [6–12] |
 Lactate level at ICU admission (mmol/L) | 3.1 [1.6–5.8] |
 Presence of septic shock at ICU admission | 261 (77) |
Use of vasoactive drugs during ICU stay | |
 Noradrenaline | 298 (88) |
 Vasopressin | 145 (43) |
 Epinephrine | 42 (12) |
 Use of medical devices during ICU stay | |
 Noninvasive positive pressure ventilation (NPPV) | 27 (8) |
 High flow nasal cannula (HFNC) | 57 (17) |
 Invasive mechanical ventilation (IMV) | 208 (61) |
 Renal replacement therapy (RRT) | 136 (40) |
Clinical consequences of hospital stay | |
 ICU mortality | 39 (12) |
 Duration of invasive mechanical ventilation | 5.0 [2.8–10.0] |
 Length of ICU stay (days) | 6.1 [3.7–10.8] |
 Length of Hospital stay (days) | 28.7 [16.5–51.5] |
Number of patients who met PICS criteria at hospital discharge | |
 Incidence of PICS | 223 (66) |
 Incidence of physical dysfunction | 164 (48) |
 Incidence of cognitive dysfunction | 145 (43) |
 Incidence of mental disorder | 129 (38) |