Fig. 3

Characteristics of each protein. A Venn diagram analysis of proteins that differed significantly in the acute phase compared to the subacute phase is shown. Twenty-eight proteins were common between plasma and BALF. B Correlation chart between each protein in the acute phase and clinical information using Spearman’s correlation coefficient. C Comparison of AZGP1 in the acute plasma and BALF between survivors and non-survivors. All vertical axis values for each protein are exponentially modified protein abundance index values. D ROC curve analysis using SOFA, APACHE II, and AZGP1. AUCs were calculated and the prognostic ability of each value for hospital mortality was evaluated. BALF bronchoalveolar lavage fluid, AZGP1 Zinc-alpha2-glycoprotein, ROC receiver operating characteristic, SOFA Sequential Organ Failure Assessment score, APACHEII Acute Physiologic Assessment and Chronic Health Evaluation II, AUC area under the curve, BMI body mass index, CNN2 Calponin 2, KSR1 Kinase Suppressor of Ras 1, HPR Haptoglobin-Related Protein, VASP Vasodilator-Stimulated Phosphoprotein, TWF2 Twinfilin Actin Binding Protein 2, CFB Complement Factor B, HK1 Hexokinase 1, HLA-C Major Histocompatibility Complex, Class I, C, PSMB8 Proteasome Subunit Beta 8, PSMB4 Proteasome Subunit Beta 4, FERMT3 Fermitin Family Member 3, AZU1 Azurocidin 1, CHI3L1 Chitinase 3-Like 1, SERPINA1 Serpin Family A Member 1, ARPC3 Actin-Related Protein 2/3 Complex Subunit 3, HP Haptoglobin, AZGP1 Alpha-2-Glycoprotein 1, Zinc-Binding, SERPINA4 Serpin Family A Member 4, AFM Afamin, NME2 Nucleoside Diphosphate Kinase B, BLVRA Biliverdin Reductase A, TPI1 Triosephosphate Isomerase 1, PRDX5 Peroxiredoxin 5, GAPDH Glyceraldehyde-3-Phosphate Dehydrogenase, HSPE1 Heat Shock Protein Family E (Hsp10) Member 1, ML12B Myosin Light Chain 12B, HSPA8 Heat Shock Protein Family A (Hsp70) Member 8, HSP90AA1 Heat Shock Protein 90 Alpha Family Class A Member 1